AnnexMedAnnexMedAnnexMed
Corporate Office
USA
299 S. Main Street
Suite 1300
Salt Lake City, UT 84111
Chennai - Tower I
CeeDeeYes Tyche Towers,
Block-1 3rd Floor, Perungudi Bypass Rd, Perungudi,
Chennai - 600096
Chennai - Tower II
4th Floor, IIFL TOWERS
MGR Main Rd,
Perungudi, Chennai - 600096
Villupuram
No 9, Viswalingam Layout
Villupuram,
Tamil Nadu – 605602

340b Program Services

End-to-End 340B Program
Operations & Audit Readiness

AnnexMed delivers 340B program integrity as ten integrated services — eligibility determination, mixed-use reconciliation, TPA management, duplicate discount prevention, and audit-ready documentation across every covered entity transaction. Audit-ready from day one.

ZERO HRSA

Audit findings

CONTINUOUS

Reconciliation

ALL MAJOR

Tpas supported

340B Program Integrity Is a Continuous Operation, Not an Annual Exercise

For a mid-size covered entity, 340B savings represent $3M–$15M+ annually — and the documentation, eligibility, and reconciliation discipline required to protect those savings runs continuously, not quarterly. Manufacturer policy changes on contract pharmacy, HRSA audit findings, and rising duplicate discount scrutiny can erode savings overnight if the operational layer is not built for the real cadence.

AnnexMed delivers 340B program support as ten integrated services running on a single operational layer. The same team handles eligibility, mixed-use, TPA reconciliation, audit preparation, and savings reporting — with shared data, unified accountability, and audit-ready documentation as a byproduct of normal operations.

Explore each service below to see how AnnexMed handles it, the typical impact, and how it integrates with your covered entity’s 340B program.
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Trusted by 100+ healthcare providers | AAPC, AHIMA & AAHAM Certified | SOC 2 Type II

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Why it matters

Why 340B Compliance and 340B Savings Belong on the Same Team?

Most covered entities split 340B operations across multiple vendors — one for software, one for TPA, one for audit consulting, one for legal support. Each vendor sees a slice of the program, none sees the whole, and the operational discipline required for continuous integrity falls through the gaps between them.
AnnexMed integrates 340B compliance and 340B savings into one operation. Encounter eligibility, mixed-use reconciliation, contract pharmacy management, duplicate discount prevention, and audit readiness all run on the same data, with the same team accountable for both protecting savings and defending them. The result: zero HRSA audit findings across the client base, continuous reconciliation instead of quarterly catch-up, and savings recovery that fragmented vendor models routinely miss.

340b Program Services

Encounter Eligibility Determination

Patient and encounter-level 340B eligibility determination with full audit trail. Provider relationship validation, encounter documentation, and prescription origination tied to eligible covered entity service.

Mixed-Use Account Reconciliation

Real-time mixed-use ratio tracking and account reconciliation across inpatient, outpatient, and ambulatory settings. Drug-specific routing logic for accurate 340B vs. non-340B accounting.

Contract Pharmacy TPA Management

Third-party administrator coordination across Apexus, SUNRx, Verity Solutions, Sentry Data Systems, and other major 340B TPAs. Daily reconciliation, discrepancy resolution, and chargeback recovery.

Duplicate Discount Prevention

Automated NDC and encounter-level duplicate discount detection to prevent the most consequential 340B compliance violations. Pre-claim alerts and post-claim audit sweeps.

Manufacturer Restriction Tracking

Active tracking of pharmaceutical manufacturer contract pharmacy restrictions, with workflow for dispute filing, resubmission, and protected access strategies as restrictions evolve quarter to quarter.

HRSA Audit Preparation

Pre-organized audit packages by NDC, encounter, provider, and date. Documentation completeness validation against current HRSA guidance. Mock audit reviews and gap remediation.

Annual Recertification

End-to-end 340B annual recertification support: covered entity documentation, provider relationship verification, contract pharmacy attestations, and 340B OPAIS database updates.

Savings Tracking & Reporting

Real-time 340B savings tracking by NDC, provider, facility, and contract pharmacy. Monthly board-ready savings reports and benchmark comparisons against covered entity peer cohorts.

Chargeback Management

Wholesaler chargeback monitoring, reconciliation, and recovery on 340B-purchased inventory. Discrepancy investigation across wholesaler, manufacturer, and TPA data sources.

Virtual Inventory Management

Virtual inventory replenishment monitoring across split-billing software platforms — accumulation tracking, replenishment order accuracy, and inventory-to-dispensing reconciliation.

Audit-Ready as a Byproduct of Operations

Every 340B transaction is documented, reconciled, and archived against current HRSA guidance during normal operations — so audits become routine reviews, not emergencies. No more pulling documentation under pressure.

Continuous Reconciliation, Not Quarterly Catch-Up

Mixed-use ratios, TPA discrepancies, and manufacturer restrictions are reconciled in real time. Issues surface within 72 hours, not 90 days — when they can still be corrected before revenue and savings get lost.
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Ready to Protect Your 340B Savings and Recover What's Been Lost?

Most covered entities identify $1M–$3M+ in unreported savings, duplicate discount exposure, and TPA reconciliation gaps in their first 340B assessment. Schedule a no-obligation 340B Program Assessment.

Trusted by 100+ Healthcare Providers | AAPC, AHIMA & AAHAM Certified | SOC 2 Type II | HIPAA Compliant

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Payer client outcomes

AnnexMed delivers measurable financial impact within the first 60 to 90 days of engagement. The following represent outcomes from active payer partnerships:

$15M–$40M

Risk
Adjustment

$18M–$50M

Payment
Integrity

6 Weeks

Credentialing Clearance

$15M–$50M+

Revenue
Impact

Case Studies

See the impact we deliver

Discover how AnnexMed reduces denials, accelerates reimbursements, and strengthens financial performance. Backed by measurable outcomes and proven RCM expertise, we deliver operational excellence, revenue stability, and sustainable growth you can trust.

Client Voices

See how our clients succeed

Hear from organizations that trust AnnexMed to reduce denials, accelerate reimbursements, and strengthen cash flow. Our expert support delivers measurable performance gains, operational efficiency, financial stability, and scalable growth.
Claims adjudication backlogs were delaying provider payments and increasing complaint volumes. AnnexMed took over processing, cleared the backlog in 30 days, and improved turnaround by 45%. Provider satisfaction scores climbed significantly, dispute volumes dropped, and our network relationships strengthened significantly.
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Dr. Richard Calloway

Horizon Health Plan
Our payer operations team was overwhelmed with member inquiries, provider disputes, and claims rework. AnnexMed brought dedicated support that handled every function with accuracy and speed. Processing errors dropped by 60%, provider abrasion decreased, and our operational costs came down by nearly a third.
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Dr. Priya Menon

Crestview Insurance Partners
Managing claims accuracy, provider data, and member support internally was draining our resources. AnnexMed streamlined our payer operations end to end. Claims processing improved, provider onboarding accelerated, and our administrative burden reduced dramatically. They understand payer complexity like no other partner.
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Laura Simmons

Meridian Managed Care

Proven RCM expertise. Delivered at scale.

For over 20 years, AnnexMed has delivered RCM solutions nationwide, combining expert billing, coding, and AR support to drive measurable results and growth.

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